Objective To study the phenotype of RhD variants in Yinchuan. Methods RhD negative blood donors screened by saline method were confirmed as weak D（partial D）by indirect antiglobulin test（IAT）. IAT negative blood donors were confirmed as Rh Del by absorption and elution test. Rh microtube column agglutinatior was used to identify Rh phenotype. Results Among 509 RhD negative blood donors, 93（18.3%）Rh D variants were identified, including 35（6.9%）weak D（partial D）, 58（11.4%）DeL and 416（81.7%）RhD negative.The distribution of Rh phenotype was as followed, 35 weak D（partial D）:ccEe 19（54.29%）,CcEe 6（17.14%），Ccee 5（14.29%），ccee 3（8.57%），CCee 2（5.71%）.58 DeL：ccEe 23（39.66%），CcEe 11（18.97%），ccee 11（18.97%），CCee 8（13.79%），CCEe 3（5.17%），ccEE 2（3.45%）. Conclusion The rate of D variants is high in Yinchuan, so this part of the blood donors determining positive which sent to the clinical can ensure blood transfusion safety. At the same time should also pay attention to C, c, E, e antigen identification