| 摘要: |
| 目的：分析肇庆地区腹泻患儿 A 群轮状病毒感染情况并探讨其发病规律。方法：采用单克隆抗体免疫胶体金技术对2116例腹泻患者的新鲜粪便中的A群轮状病毒抗原进行检测，并对RV阳性标本进行粪便常规检查和隐血试验。结果：2116例腹泻患者中A群轮状病毒阳性的有446例，阳性率为21.08%，其中6个月~2岁、2岁~3岁和3岁~5岁这三个年龄段阳性率最高，分别为26.75%、22.91%和21.6%；男女患儿RV阳性率差异无统计学意义 （Ｐ>0.05）;1、2、3月份间RV阳性率分别为46.42%、42.06%、38.07%，明显高于其他月份。城镇患儿（12.26%）与农村患儿（13.13%）的RV阳性率差异无统计学意义（Ｐ>0.05）。446例RV阳性患者中，粪便常规检查和隐血试验阴性361例，占80.98%；隐血试验阳性61例，占13.17%；镜下白细胞和红细胞阳性各占2.68%和0.48%，少量白细胞（<5个/HP）18例，占3.9%。结论：A群轮状病毒相关性腹泻的发生具有明显的地区和季节差异，应根据其易感人群、流行时间作出准确的诊断及治疗。 |
| 关键词: A群轮状病毒 腹泻 粪便 |
| DOI：0 |
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| Analysis of GroupA rotavirus infection among people with diarrhea |
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| Abstract: |
| Objective :To investigate the prevalence of Group－A rotavirus infection among children with diarrhea of Zhaoqing Area in Guangdong Province,and to explore its pathogenesis regularity.Methods: Fresh excreta samples of 2116 patients with diarrhea were collected and group－A rotavirus was detected by monoclonal antibody immune colloidal gold device.Results:446 cases(21.08%) were positive for group-A rotavirus in all the 2116 cases. The positive rates of group-A rotavirus among 6 months to 2 year ，2 to 3 years，3 to 5 years old were 26.75%,22.91% and 21.6%, which significantly intended to be the high incidence age. The infection rate in male infants was 20.32%(278/1368),versus 22.46%(168/748) in the female.The positive rates of group-A rotavirus among children during January, February and March were 46.42%,42.06% and 38.07%, which significantly higher than the other months(P<0.05).There is no statistically significant difference of the rotavirus ’ positive rate between the patience lived in town ( 12.26%) and the rural patients (13.13%)(,Ｐ>0.05). In the 446 RV positive patients, there are 361 cases that the stool examination and OB test are both negative, accounting for 80.98%; 61 cases got the positive OB test, accounting for 13.17%; the RBCs and the WBCs that could see under a microscope each accounted for 2.68% and 0.68%,and a few WBCs (< 5 / HP) could be seen in 18 cases, accounting for 3.9%.Conclusion: Group-A rotavirus is one of the main pathogen of infant diarrhea, the occurrence of the disease mainly occurs in children aged from 6 months to 2 years old. This disease has obvious regional and seasonal differences, we should make an accurate diagnosis and treatment according to the susceptible groups, popular time. |
| Key words: A rotavirus diarrhea faeces |
